WHO adds weight-loss, diabetes drugs to essential medicines list

Along with treatments for cancer and cystic fibrosis, the World Health Organization (WHO) has updated its list of essential medicines to include medications for obesity and diabetes.

People in developing nations should also be able to purchase cheap generic versions of the glucagon-like peptide-1 (GLP-1) medications, according to a statement released on Friday.

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The WHO recommends that all functioning health systems have access to 523 medications for adults and 374 for children.

The new editions of WHO’s Health Systems, Access and Data list “mark a significant step toward expanding access to new medicines with proven clinical benefits and a high potential for global public health impact,” said Yukiko Nakatani, WHO’s assistant director-general for Health Systems, Access and Data.

To treat type 2 diabetes in combination with existing cardiovascular disease, chronic kidney disease, or obesity, the expert committee added the active ingredients to the list from Novo Nordisk’s Ozempic and Eli Lilly’s Mounjaro.

The medications, which were first developed to treat diabetes, have grown in popularity as weight-loss medications under various brand names. However, unlike in 2023, the WHO did not include them in the obesity treatment program.

According to the committee, this decision provided clear recommendations for which patients would gain the most from the treatments.

The WHO statement continued, “Medicare access is being hampered by the high prices of semaglutide and tirzepatide,” noting that encouraging generic drug makers to create the product would help when the drugs’ patents expire next year.

additions that are not already known

More than one billion people are affected by obesity, while more than 800 million people worldwide are currently living with diabetes.

The organization made plans earlier this year to recommend the use of obesity medications, which are separate from their inclusion on the essential medicines list.

More than 3.7 million people died from diseases linked to obesity or overweight in 2021, according to WHO data, more than 3.7 million of those deaths coming from malaria, tuberculosis, and HIV alone.

Additionally included on the list are Trikafta or Kaftrio, Trikafta or Trikafta, both from Vertex Pharmaceuticals. For years, activists have criticized its high price and limited accessibility.

Merck’s key-selling cancer immunotherapy drug, Keytruda, is also included in WHO’s list for the treatment of non-small cell lung cancers that have spread, or metastasizes, as well as cervical cancers, colorectal cancers, and non-small cell lung cancers that have metastasized or spread. Additionally, the organization suggested strategies to improve drug access.

UN rights chief urges US to withdraw sanctions on Palestinian NGOs

In response to the international outcry against the US action, UN Human Rights Chief Volker Turk has called for the sanctions to be lifted against Palestinian rights organizations.

Turk praised the nongovernmental organizations (NGOs) that the US has targeted for their support of the Palestinian Center for Human Rights (PCHR), the International Criminal Court for Human Rights (ICHR), and the Al-Mezan Center for Human Rights.

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These NGOs have been carrying out important human rights work for decades, he said, especially in terms of accountability for human rights violations.

I urge the US government to halt these sanctions right away.

On Thursday, US Secretary of State Marco Rubio placed sanctions on the Palestinian organizations, preventing Americans from transacting with their assets and preventing them from doing so.

Without Israel’s permission, these organizations have directly engaged in the International Criminal Court’s (ICC) investigations, arrests, detentions, or prosecutions,” according to Rubio in a statement.

He also vowed to continue to “respond with significant and tangible consequences” to ICC prosecution efforts against Israeli officials.

The administration of US President Donald Trump’s wider campaign aims to punish Israel’s critics both domestically and internationally.

Washington has placed sanctions on a number of ICC&nbsp, judges and officials, as well as UN rapporteur Francesca Albanese, who has been attempting to hold accountable for Israel’s violations over the past few months.

Israeli Prime Minister Benjamin Netanyahu and his former defense minister Yoav Gallant were detained by the ICC last year on suspicion of using starvation as a weapon of war.

Under the leadership of then-President Joe Biden, the US quickly refuted the accusations, arguing that Israel was not a signatory to the Rome Statute, which established the ICC.

The state of Palestine, which joined the court in 2015, was the state that the court claimed was competent to prosecute alleged war crimes committed in Gaza.

Rubio’s statement on Thursday reiterated the US position.

The top US diplomat said, “This administration has made it clear that the United States and Israel are not under the authority of the ICC.”

The UN’s Turk, on the other hand, claimed that the US move promotes “a climate of continued commission of violations and international crimes” and encourages impunity.

According to him, “these attacks on NGOs that work to advance the respect for human rights directly conflict with the US’s long-held and promoted rule of law and other values.” The sanctions will have a chilling impact on Israeli civil society in the occupied Palestinian territory and in Israel, as well as potentially on the entire world.

A coalition of Palestinian and Israeli rights organizations, including B’Tselem, released a statement supporting the alleged NGOs earlier on Friday.

Chicago braces for possible National Guard deployment: What we know

Officials in the US city of Chicago were bracing for a possible deployment of the United States National Guard on Friday, as part of President Donald Trump’s wider crackdown on crime and immigration – notably, many point out, in Democratic strongholds.

Last week, CNN, citing unnamed officials, reported that the controversial military deployment could take place by Friday and that the National Guard might be ready to patrol the city on Saturday.

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At the same time, a major federal immigration operation involving officials from Immigration and Customs Enforcement (ICE) is also expected to begin in the city.

Last Sunday, Illinois Governor JB Pritzker, a Democrat, claimed the Trump administration had not informed him of the deployment plans, and that such a move would amount to an “invasion” of the state.

On Saturday last week, Chicago’s Mayor Brandon Johnson signed an executive order directing Chicago police not to collaborate with National Guard troops or federal agents. The order also urged federal agents to wear body cameras and reveal their faces rather than wear masks, as they have done during previous, “military-style” immigration raids under Trump.

Trump deployed the National Guard in Los Angeles in June, and in Washington, DC, in August, purportedly to fight surging crime rates, but residents and state officials have complained that such moves are undemocratic and say that over-policing will erase trust between local police and communities.

National Guard troops patrol the grounds of the Washington Monument with the US Capitol seen in the distance as part of President Donald Trump’s order to impose federal law enforcement in the nation’s capital, in Washington, on Thursday, August 28, 2025 [J Scott Applewhite/AP]

What is the National Guard?

The National Guard is a state-based reserve force totalling 430,040 soldiers and airmen who are serving part-time, rather than full-time. It includes the Army National Guard and the Air National Guard units. National Guard members often hold a civilian job in addition to their military duties.

Each US state and entity has its own National Guard unit, and all together make up the US National Guard. The Guard can be activated for federal missions, such as under Trump’s recent directives, meaning it is dually-controlled by states and the federal government.

The National Guard’s origins go back to colonial-era militias that formed during British rule, with the first colony-wide militia forming in Massachusetts in 1636. Those militias later evolved into an organised, national structure following US independence.

What happened in Los Angeles?

In June, Trump deployed nearly 4,000 National Guard troops and 700 US Marines to Los Angeles to quell public protests against ICE raids. California Governor Gavin Newsom described the move as “political theatre”.

A court ruled on Tuesday that the deployment was illegal. It was the first time since 1965 that a president had federalised National Guard troops to address unrest in a state without a governor’s permission. President Lyndon B Johnson, at the time, sent troops to Selma, Alabama, to protect civil rights protesters from violence.

What happened in Washington, DC?

On August 12, Trump announced at a White House press conference that he was temporarily taking control of Washington, DC’s Metropolitan Police Department under Section 740 of the rarely invoked District of Columbia Home Rule Act, which allows federal control of police during an emergency.

Government officials said the DC force would be in place till November, according to a report on Thursday from ABC News.

Trump additionally deployed 800 National Guard troops to the city to “rescue” it from what he said was a crime and homelessness surge.

“I’m announcing a historic action to rescue our nation’s capital from crime, bloodshed, bedlam and squalor and worse,” Trump said in his announcement. “This is Liberation Day in DC, and we’re going to take our capital back.”

Trump has also said that his administration will seek the death penalty for murder cases in the city.

Washington, DC, is classified as a unique federal district and is a Democratic stronghold. As US president, Trump has direct control over the District of Columbia National Guard and can use the DC police force for 48 hours, or up to 30 days if he notifies Congress. However, Congress has not been formally notified of the recent moves.

DC Mayor Muriel Bowser initially criticised the deployment, describing it as “unsettling and unprecedented” on August 11. She added that although violent crime had spiked in the city in 2023, recent data shows crime rates have been falling and that violent crime is at a 30-year low.

Bowser has since tried to cooperate with federal agents by setting up an operations centre to coordinate communications between federal agencies and local law enforcement. The centre was established under Bowser’s “Safe and Beautiful Emergency Operations Center” (SBEOC), which is a play on Trump’s lingo.

One of the centre’s tasks is to ensure federal agents maintain policing practices that instil confidence in residents, such as not wearing masks, identifying their agencies and providing identification when interacting with people.

Despite that, on August 27, Bowser told reporters that there was a “break in trust” between communities and the police due to the presence of federal agents who wore masks and were not always identifiable. Bowser said she was “devastated” because some residents in the city said they were living in fear.

Week in Pictures
Demonstrators march as they protest against President Donald Trump’s use of federal law enforcement and National Guard troops in the US capital during a rally along the 14th Street corridor in northwest Washington, DC, Saturday, August 30, 2025 [Jose Luis Magana/AP]

Why does Trump say it is necessary to deploy troops to cities?

Trump has argued that it is essential to combat crime in Los Angeles, DC and other cities. Despite widespread criticism and legal challenges, he has defended his decision, saying some troublemakers have to be handled by soldiers.

“Frankly, they were born to be criminals,” Trump said on Wednesday, when he confirmed the Chicago deployment would happen but did not give dates. “And they’re tough and mean, and they’ll cut your throat, and they won’t even think about it the next day. They won’t even remember that they did it. And we’re not going to have those people.”

The president has also pointed to what he says are the positive results from the DC federal takeover. Speaking at a conference on Tuesday, Trump said the city was now safe and that restaurants were enjoying booming businesses.

“We have no crime,” Trump said. “You’re not going to be shot.”

Republican lawmakers have backed Trump’s actions, especially in DC, where some are proposing a “Make Our Streets Safe Again Act” to target crime and address homelessness.

“President Trump’s unyielding leadership and strength, coupled with proper congressional oversight, ensures that Washington, DC, will reclaim its rightful place,” US Representative Harriet Hageman, a Republican, said at a news conference on Tuesday.

Where else has Trump threatened to deploy the National Guard?

Trump and officials from his administration have floated possible plans to deploy the National Guard in Democratic-led cities including Chicago, Baltimore, Boston and New York.

On Tuesday, Trump stated at a conference that he has “an obligation to protect this country, and that includes Baltimore”.

On August 22, he told reporters in the Oval Office that “Chicago is a mess”, and that his administration “will help with New York”.

The day before, ICE’s acting director said agents would “flood” Boston to remove immigrants in the so-called “sanctuary city”, referring to municipalities that limit cooperation with federal law enforcement on immigration issues.

Officials in Baltimore and Chicago, meanwhile, insist that crime rates have fallen in their cities.

In July, Baltimore’s police department said there had been a significant drop in gun violence compared to last year. The city’s Mayor Brandon Scott also told reporters on Monday that by September 1, 2025, 91 homicides and 218 non-fatal shootings were recorded. He said it was the lowest yearly homicide rate in over 50 years.

Also on Monday, Chicago Mayor Brandon Johnson said at a conference that overall crime rates had fallen in the city by 21 percent. “We will not have our police officers, who are working hard every single day to drive down crime, deputise to do traffic stops and checkpoints for the president,” he said.

How bad is crime in Chicago?

With a population of 2.7 million, Chicago has long had a national reputation linked with high crime rates, particularly gun violence. Legal experts say that reputation has some basis, but that crime rates are not unconnected to the era of racial segregation.

In reality, however, crime rates in Chicago vary depending on the crime type, and generally mirror those in other major cities, according to analysis by CBS News, which cited data from the Chicago Police and the FBI.

Last year, the city had 18,327 reported cases of violent crime, which translates to 695 per 100,000 people. In comparison, Oakland had 1,925 cases per 100,000; Detroit, 1,781; Little Rock, 1,672; and Baltimore, 1,606. Houston, which has a smaller population of 2.3 million, recorded a total of 26,628 violent crimes or 1,148 crimes per 100,000.

According to data from the DC-based Council on Criminal Justice (CJC), Chicago did see a 369 percent [nearly fivefold] increase in violent crime, property and drug offences between 2019 and 2023, driven mainly by a surge in vehicle thefts that was recorded in several other large cities in the same period. Many US cities similarly recorded high crime rates during the COVID-19 pandemic.

More recently, the CCJ reported that overall crime in Chicago by June 2025 was down compared to 2024.

In a year-on-year analysis, the CCJ noted that violent crimes such as homicides had reduced by 33 percent compared to last year. Aggravated assaults fell by 16 percent, gun assaults by 27 percent, robberies by 35 percent, carjacking by 51 percent and domestic violence by 10 percent.

An exception to the downward trend was sexual assault cases, which only reduced by one percent between June 2024 and June 2025.

What do critics of Trump’s hardline approach say?

Trump’s deployment of troops in Los Angeles, Washington, DC, and the looming Chicago deployment have faced criticism and legal challenges from law experts, officials and residents. Some say it constitutes the formation of a “police state”, the sidelining of state authorities, and overreach. Others say it is over-policing that could have an adverse impact on relations between communities and local law enforcement.

“This is an active military takeover of the capital,” protesters who assembled outside Congress in DC on Thursday wrote in an open letter to lawmakers, which they handed out.

“It is a textbook indicator of backsliding democracy and intensifying authoritarianism … This might come off as alarmist, but in the last 100 years of history, the pattern is clear and we are witnessing it in real time,” the letter stated.

California Governor Gavin Newsom and the state’s Attorney General Rob Bonta have also argued that Trump’s decision to deploy federal military agents violates the Posse Comitatus Act, which restricts the use of the military for civilian law enforcement.

This week, US District Judge Charles Breyer ruled that the Los Angeles deployment was unprecedented, an overstep of presidential authority, and ultimately, illegal. The case had been filed in June by the state of California.

“There were indeed protests in Los Angeles, and some individuals engaged in violence,” Breyer wrote, referring to Trump’s insistence that the anti-immigration-raid protests constituted a “rebellion” that needed to be quashed.

“Yet there was no rebellion, nor was civilian law enforcement unable to respond to the protests and enforce the law,” Breyer wrote in his judgement.

UK deputy prime minister resigns amid tax scandal

Angela Rayner, the deputy prime minister of the United Kingdom, resigned after a probe revealed she had lied about paying her flat’s tax, leading to a wider cabinet reshuffle and furthering the Labour Party’s woes.

In a letter to Keir Starmer, the prime minister, Rayner said she “did not meet the highest standards” and would step down from her positions as deputy leader of Labour and housing minister.

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Rayner, who admitted to underpaying a surcharge on the flat last week, “regrets a lot that I don’t seek additional specialist tax advice.” She claimed that she accepted full responsibility for the error.

Starmer responded that his party would be devastated to lose her from the government, but added that she would continue to be a significant force.

Starmer’s government has endured a number of crises since taking office in July 2024, and it now trails hard-right firebrand Nigel Farage’s Reform UK party in national polls. Rayner was popular with working-class voters and a skilled mediator between Labour’s left and centrist wings.

According to Birmingham-based Jonah Hull of Al Jazeera, Keir Starmer loses “perhaps the closest link the Labour Party has to its working-class roots” in losing her.

Shortly before UK media reported that Lucy Powell, the head of the House of Commons, and Ian Murray, the head of Scotland, both had been fired.

Powell claimed in a post on X that Starmer had informed her that he intended to appoint a new Commons leader.

The government has not had a good time this time. People want to see better and more difficult lives being led, according to Powell.

Complexity in the Rayner tax scandal

Following days of reports that claimed she had saved £40, 000 ($53, 000) by removing her name from the deeds of another property, Rayner admitted on Wednesday that she had underpaid the so-called stamp duty on a seaside flat in southern England.

Ethics chief Laurie Magnus acknowledged that Rayner had twice been informed that the lower rate of stamp duty was applicable and that the rules “entailed a significant degree of complexity” after looking into the case.

However, the fact that it was acknowledged to not be expert tax advice qualified that recommendation.

She “cannot be said to have met the highest possible standards of proper conduct” due to Rayner’s failure to seek further guidance, according to Magnus.

Rayner has frequently been projected to lead the Labour Party and has become a frequent target of political attacks from the Conservatives and the right-wing media.

On September 4, 2025, Angela Rayner’s second property in Hove, United Kingdom, is depicted in graffiti that reads “tax evader.” [Carlos Jasso/Reuters]