Amy Schumer explains 50 pounds weight loss ‘Not to Look Hot’ but ‘to Survive’ deadly disease
Hollywood star Amy Schumer has detailed the life-threatening health condition that has shaped her recent weight loss.
Addressing speculation in a new social media post filmed by her six-year-old son, the 44-year-old comedian shared an Instagram Reel. The footage, beginning as she lounged in bed before her son Gene, whom she shares with her husband Chris Fischer, took viewers on a brief tour of their home.
While the video itself was upbeat, Schumer used on-screen text to respond to ongoing commentary about her appearance and the circumstances behind her weight loss. She rejected claims she had used cosmetic procedures as part of her transformation, writing: “I don’t get Botox or filler,” and clarified that she had lost far more weight than reported.
“Despite reports she didn’t lose 30 lbs., she lost 50,” she said, adding: “Not to look hot which does feel fun and temporary. I did it to survive.”
Schumer went on to explain that her weight loss followed treatment for what she described as a potentially life-threatening illness.
“I had a disease that makes your face extremely puffy that can kill you, but the internet caught it, and the disease has cleared,” she wrote, in an apparent reference to her diagnosis of Cushing syndrome earlier this year.
Cushing syndrome occurs when the body is exposed to too much cortisol, the primary stress hormone. According to the Mayo Clinic, symptoms can include a rounder, fuller face, significant weight gain concentrated around the torso, elevated blood pressure and rapid changes to the skin, including stretch marks. The condition can be dangerous if untreated.
The comedian acknowledged that her changing appearance had prompted strong reactions online. “Sorry for whatever feeling it’s giving you that I lost that weight,” she wrote. Schumer also reiterated that she has undergone plastic surgery “over the years” and disclosed that she “uses Mounjaro,” a prescription medication increasingly used for diabetes and weight management.
“Sorry to anyone that lets down,” she added.
Despite the scrutiny, she said her health has now markedly improved, writing that she is “pain free” and can “can [play] tag” with her son. Schumer also used the post to discuss her ongoing experience of perimenopause, which she revealed in February 2024 she was going through alongside her long-standing endometriosis. “Happy to share if anyone has any questions about how I’m looking or feeling or where I am in my perimenopause process,” she said.
Perimenopause, the transitional stage before menopause, typically involves fluctuating levels of oestrogen and can lead to symptoms such as hot flashes, sleep disruptions and irregular periods, according to the Cleveland Clinic.
The phase can last for several years.
The actor additionally addressed public speculation surrounding her marriage. “Whatever ends up happening with Chris has nothing to do with weight loss or autism,” she wrote, referring to her husband’s autism diagnosis. “Fingers crossed we can make it through, he’s the best.”
Reports circulated last month suggesting the couple were facing challenges, but a source close to Schumer and Fischer, 45, said the pair “remain committed to their relationship” and are “privately working through normal issues that couples in long-term marriages have.”
The source added: “They are both committed to the relationship.” Schumer has previously pushed back against rumours regarding her marriage.
Source: Mirror
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